We have a couple of clients on the early adopters program from Microsoft for Dynamics (GP) 2010.
We have hit our first issue, this only effects non U.S. installs and is a re occurrence of an issue from version 10.
The problem is installing Business portal. It won’t install on non U.S. regional settings. You need to change your regional settings to U.S., install BP and then change them back to U.K. or where ever else you are in the world. This was a problem in BP4 for version 10 and its still there in BP5 for version 2010 (beta).